2’,3’,5’-Tri-O-benzoyl-5-hydroxy methyluridine (see GL100342)

Names

[ Name ]:
2’,3’,5’-Tri-O-benzoyl-5-hydroxy methyluridine (see GL100342)

[Synonym ]:
2',3',5'-Tri-O-benzoyl-5-(hydroxymethyl)uridine
Uridine, 5-(hydroxymethyl)-, 2',3',5'-tribenzoate

Biological Activity

[Description]:

2’,3’,5’-Tri-O-benzoyl-5-hydroxy methyluridine (see GL100342) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₃₁H₂₆N₂O₁₀

[ Molecular Weight ]:
586.55

[ Exact Mass ]:
586.158752

[ LogP ]:
2.36

[ Index of Refraction ]:
1.670