9-ALPHA-RIBOFURANOSYLADENINE

Names

[ CAS No. ]:
5682-25-7

[ Name ]:
9-ALPHA-RIBOFURANOSYLADENINE

[Synonym ]:
α-D-adenosine
A-ADENOSINE
(1S)-1-(6-Amino-purin-9-yl)-D-1,4-anhydro-ribit
α-Adenosine
1-(6-amino-purin-9-yl)-α-L-1-deoxy-ribofuranose
ALPHA-ADENOSINE
α-adenosine
9-ALPHA-RIBOFURANOSYLADENINE
9H-PURIN-6-AMINE, 9-A-D-RIBOFURANOSYL-
1-α-D-ribofuranosyladenine

Biological Activity

[Description]:

Alpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Melting Point ]:
205-207 °C

[ Molecular Formula ]:
C10H13N5O4

[ Molecular Weight ]:
267.24

[ Exact Mass ]:
267.09700

[ PSA ]:
139.54000

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T+

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds