2’,3’-Bis-(O-t-butyldimethylsilyl)uridine

Names

[ CAS No. ]:
69504-12-7

[ Name ]:
2’,3’-Bis-(O-t-butyldimethylsilyl)uridine

Biological Activity

[Description]:

2’,3’-Bis-(O-t-butyldimethylsilyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H40N2O6Si2

[ Molecular Weight ]:
472.72

Related Compounds