5'-DMTr-2,2'-anhydrothymidine

Names

[ Name ]:
5'-DMTr-2,2'-anhydrothymidine

[Synonym ]:
2,2'-anhydro-1-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl-5-methyluridine]

Biological Activity

[Description]:

5'-DMTr-2,2'-anhydrothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₀N₂O₇

[ Molecular Weight ]:
542.58

[ Exact Mass ]:
542.20500

[ PSA ]:
101.27000

[ LogP ]:
3.59690

5'-DMTr-2,2'-anhydrothymidine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds