8-Methyl-2’-deoxyguanosine

Names

[ CAS No. ]:
85819-69-8

[ Name ]:
8-Methyl-2’-deoxyguanosine

[Synonym ]:
Guanosine,2'-deoxy-8-methyl

Biological Activity

[Description]:

8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H15N5O4

[ Molecular Weight ]:
281.27

[ Exact Mass ]:
281.11200

[ PSA ]:
140.27000

Precursor & DownStream

Precursor

DownStream