Tankyrase-IN-3

Names

[ CAS No. ]:
938893-79-9

[ Name ]:
Tankyrase-IN-3

Biological Activity

[Description]:

Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 22 nM. Tankyrase-IN-3 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> PARP

Signaling Pathways >> Cell Cycle/DNA Damage >> PARP

[Target]

TNKS1:22 nM (IC50)

[In Vitro]

Tankyrase-IN-3 具有 TNKS1 抑制活性，IC50 值为 22 nM[1]。

[References]

[1]. Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₁N₅O₄

[ Molecular Weight ]:
407.42

Related Compounds