95416-30-1

95416-30-1 structure

Name: H-Gly-Gly-Cys-OH
Chemical Name: (2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid
CAS Number: 95416-30-1
Molecular Formula: C₇H₁₃N₃O₄S
Molecular Weight: 235.26
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-01-04 20:35:10
Modify Date: 2024-01-14 16:50:04
Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin[1].

Name	(2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid
Synonyms	Glycyl-glycyl-cysteine Gly-gly-cys

Description	Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
Target	IC50: 9.4 μM (TAFI) Ki: 0.99 μM (TAFI)[1]
References	[1]. Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71.