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54417-53-7

54417-53-7 structure
54417-53-7 structure
  • Name: R-Tetrahydropapaverine
  • Chemical Name: R-Tetrahydropapaverine
  • CAS Number: 54417-53-7
  • Molecular Formula: C20H26ClNO4
  • Molecular Weight: 379.88
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-09-06 22:54:34
  • Modify Date: 2024-01-11 16:41:54
  • (R)-Tetrahydropapaverine hydrochloride is the inactive isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].

Name R-Tetrahydropapaverine
Synonyms (R)-(-)-Norlaudanosine Hydrochloride
(R)-1-((3,4-dimethoxyphenyyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline hydrochloride
MFCD03788189
(R)-Tetrahydropapaverinehydrochloride
EINECS 415-110-8
R-(+)-TETRAHYDROPAPAVERIN HYDROCHLORIDE
http://www.gabrielpharm.com/hy/detailpro.phpid=39
(R)-1,2,3,4-tetrahydropapaverine hydrochloride
(R)-tetrahydropaverine hydrochloride
Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1)
(R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
D-(-)-Norlaudanosine hydrochloride
(R)-1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL
R-BINAP
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1)
R-(+)-Tetrahydropapaverin
(r)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline
R-(-)-norlaudanosine*HCl
R-tetrahydropapaverine HCl
Description (R)-Tetrahydropapaverine hydrochloride is the inactive isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].
Related Catalog
References

[1]. Koshimura I, et al. Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system. Brain Res. 1997 Oct 31;773(1-2):108-16.  

[2]. Kim EI, et al. Inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in murine mastocytoma P815 cells. Life Sci. 2004 Sep 3;75(16):1949-57.  

Density 1.12 g/cm3
Boiling Point 475.8ºC at 760 mmHg
Molecular Formula C20H26ClNO4
Molecular Weight 379.88
Flash Point 202.7ºC
Exact Mass 379.155029
PSA 48.95000
LogP 4.28130
Index of Refraction 1.549
Hazard Codes Xn:Harmful;
Risk Phrases R22;R52/53
Safety Phrases S22-S61
HS Code 2933499090

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54417-53-7 structure

54417-53-7

Literature: WO2009/106547 A1, ; Page/Page column 9-10 ;

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54417-53-7 structure

54417-53-7

Literature: Tetrahedron Letters, , vol. 22, # 39 p. 3869 - 3872
Precursor  2

DownStream  0

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%