7081-40-5

7081-40-5 structure

Name: Metixene hydrochloride hydrate
Chemical Name: methixene hydrochloride
CAS Number: 7081-40-5
Molecular Formula: C₂₀H₂₆ClNOS
Molecular Weight: 363.94500
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-09-25 14:41:12
Modify Date: 2024-01-23 17:52:16
Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].

Name	methixene hydrochloride
Synonyms	1-Methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine hydrochloride hydrete Methixene hydrochloride hydrete Methixene hydrochloride hydrate

Description	Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	IC50: 55 nM (mAChR)[1] Ki: 15 nM (mAChR)[1]
In Vitro	Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].
References	[1]. Syvälahti EK, et al. Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol. 1988 Feb;62(2):90-4.

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%