Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (+/-)-4-Hydroxy Mephenytoin
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-HYDROXY MEPHENYTOIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

61837-65-8

61837-65-8 structure

61837-65-8 structure

Name: (+/-)-4-Hydroxy Mephenytoin
Chemical Name: (+/-)-4-Hydroxy Mephenytoin
CAS Number: 61837-65-8
Molecular Formula: C₁₂H₁₄N₂O₃
Molecular Weight: 234.251
Catalog: Research Areas Others
Create Date: 2018-05-28 08:00:00
Modify Date: 2024-01-01 18:04:54
4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.

Name	(+/-)-4-Hydroxy Mephenytoin
Synonyms	4-hydroxy mephenytoin 5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione 5-Ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione 2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl- 4-Hydroxymephenytoin

Description	4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
In Vitro	4-Hydroxymephenytoin is a metabolism of mephenytoin, which is an antiepileptic drug, and used as a CYP2C19 substrate[1]. 4-Hydroxymephenytoin (4'-Hydroxymephenytoin) is used for developing UltraPerformance LC (UPLC) tandem mass spectrometry assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples[2].
References	[1]. Tanaka M, et al. Simple and selective assay of 4-hydroxymephenytoin in human urine using solid-phase extraction and high-performance liquid chromatography with electrochemical detection and its preliminary application to phenotyping test. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):87-94. [2]. Stewart NA, et al. A UPLC-MS/MS assay of the "Pittsburgh cocktail": six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilution. Analyst. 2011 Feb 7;136(3):605-12.

Density	1.3±0.1 g/cm3
Melting Point	153-154ºC
Molecular Formula	C₁₂H₁₄N₂O₃
Molecular Weight	234.251
Exact Mass	234.100449
PSA	69.64000
LogP	0.66
Index of Refraction	1.568
Storage condition	2-8℃

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	UN1230 - class 3 - PG 2 - Methanol
Flash Point(F)	48.2 °F
Flash Point(C)	9 °C