536709-33-8

536709-33-8 structure

Name: Ezetimibe Hydroxy Glucuronide
Chemical Name: Ezetimibe Hydroxy β-D-Glucuronide
CAS Number: 536709-33-8
Molecular Formula: C₃₀H₂₉F₂NO₉
Molecular Weight: 585.55
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-06-21 17:40:52
Modify Date: 2024-01-11 18:54:17
Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376)[1].

Name	Ezetimibe Hydroxy β-D-Glucuronide
Synonyms	(2S,3S,4S,5R,6R)-6-[(1S)-1-(4-fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]propoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

Description	Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Anima Ghosal, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20. [2]. Ghosal A, et al. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Dispos. 2004 Mar;32(3):314-20.