30861-27-9

30861-27-9 structure

Name: Aloesin
Chemical Name: 7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
CAS Number: 30861-27-9
Molecular Formula: C₁₉H₂₂O₉
Molecular Weight: 394.373
Catalog: Research Areas Cancer
Create Date: 2018-07-13 18:09:12
Modify Date: 2024-01-03 14:59:58
Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].

Name	7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Synonyms	Aloe resin B 4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)- Aloersin B (1S)-1,5-Anhydro-1-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]-D-glucitol D-Glucitol, 1,5-anhydro-1-C-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-1-benzopyran-8-yl]-, (1S)- Aloesin

Description	Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Zhang LQ, et al. Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells through the Inhibition of the MAPK Signaling Pathway. Anal Cell Pathol (Amst). 2017;2017:8158254. [2]. Wahedi HM, et al. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo. Phytomedicine. 2017 May 15;28:19-26.

74545-79-2

30861-27-9

7400-08-0

Literature: CSIR, BIO/CHEMTEK Patent: WO2006/97811 A1, 2006 ; Location in patent: Page/Page column 5; 8-10 ;