508-01-0

508-01-0 structure

Name: Soyasapogenol A
Chemical Name: Soyasapogenol A
CAS Number: 508-01-0
Molecular Formula: C₃₀H₅₀O₄
Molecular Weight: 474.71600
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-04-01 08:00:00
Modify Date: 2024-01-04 12:08:14
Soyasapogenol A, a triterpene compound, isolated from the roots of Abrus cantoniensis. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].

Name	Soyasapogenol A
Synonyms	soya sapogenol a soyasapogenol a(p)

Description	Soyasapogenol A, a triterpene compound, isolated from the roots of Abrus cantoniensis. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Inflammation/Immunology
References	[1]. Chiang TC, et al. Isolation and structural elucidation of some sapogenols from Abrus cantoniensis. Planta Med. 1982 Sep;46(1):52-5. [2]. Kuzuhara H, et al. Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model. Eur J Pharmacol. 2000 Mar 10;391(1-2):175-81.