25425-12-1

25425-12-1 structure

Name: (-)-Citreoviridin
Chemical Name: (-)-citreoviridin
CAS Number: 25425-12-1
Molecular Formula: C₂₃H₃₀O₆
Molecular Weight: 402.481
Catalog: analytical chemistry Standard Food and cosmetics standards
Create Date: 2018-02-17 08:00:00
Modify Date: 2024-01-08 14:22:59
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner[1]. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells[2].

Name	(-)-citreoviridin
Synonyms	Citreoviridin 2,5-Anhydro-1,6-dideoxy-2-[(1E,3E,5E,7E)-8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1,3,5,7-octatetraen-1-yl]-4-C-methyl-D-iditol CITREOVIRIDIN BIOCHEMICA Citreoviridin A L-arabino-Hept-5-enitol, 1,4-anhydro-5,6,7-trideoxy-6-[(1E,3E,5E)-6-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-1,3,5-hexatrien-1-yl]-1,2,4-tri-C-methyl-, (1R,5E)-

Description	Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner[1]. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cardiovascular Disease Research Areas >> Infection
Target	Na+/K+-ATPase[1] Apoptosis[2]
References	[1]. Datta SC, et al. Effect of citreoviridin, a mycotoxin from Penicillium citreoviride, on kinetic constants of acetylcholinesterase and ATPase in synaptosomes and microsomes from rat brain. Toxicon. 1981;19(4):555-62. [2]. Hou H, et al. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells. Environ Toxicol Pharmacol. 2014 Mar;37(2):828-36.