Name | methoxypoly(ethylene glycol) |
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Synonyms |
MFCD00084416
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy- Polymer 2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-ol Methoxypolyethylene glycols |
Description | m-PEG-OH (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.08 |
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Boiling Point | 557.1±45.0 °C at 760 mmHg |
Melting Point | 12 ºC |
Molecular Formula | C23H48O12 |
Molecular Weight | 516.620 |
Flash Point | 268 ºC |
Exact Mass | 516.314575 |
LogP | -4.38 |
Appearance | semisolid | White to pale yellow |
Vapour density | >1 (vs air) |
Vapour Pressure | 0.0±3.4 mmHg at 25°C |
Index of Refraction | 1.456 |
Storage condition | ?20°C |
Water Solubility | H2O: 50 mg/mL at 25 °C, clear, colorless |