2140-72-9

2140-72-9 structure

Name: 2′-O-methylcytidine
Chemical Name: 2'-O-methylcytidine
CAS Number: 2140-72-9
Molecular Formula: C₁₀H₁₅N₃O₅
Molecular Weight: 257.243
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-02-20 08:00:00
Modify Date: 2024-01-04 13:11:27
2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate[1].

Name	2'-O-methylcytidine
Synonyms	2'-OMe Cytidine 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one 2'-OMeCytidine 2'-O-Methyl-D-cytidine 2’-O-Methyl Cytidine O2'-methylcytidine 4-Amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydro-2-furanyl]-2(1H)-pyrimidinone 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-on Cytidine, 2'-O-methyl- 2'-OMe-C 2'-O-methyl-2'-deoxy-cytidine 2′-O-methylcytidine MFCD00056067 2'-O-Methylcytidine 2&#39-O-Methylcytidine 2'-O-methyl-cytidine 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one 2'-O-(TERT-BUTYLDIMETHYLSILYL)-6A-HYDROXY-7-EPI-PACLITAXEL

Description	2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection
References	[1]. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%