Name | 1-Benzylimidazole |
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Synonyms |
1-BENZYL IMIDAZOLE
MFCD00005296 Imidazole,1-benzyl 1H-Imidazole, 1-(phenylmethyl)- 1-benzylimidazole 1H-Imidazole, 1- (phenylmethyl)- BENZYLIMIDAZOLE 1-Benzyl-1H-imidazole N-benzylimidazole EINECS 224-200-4 3-Benzylimidazole |
Description | 1-Benzyl-1H-imidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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Related Catalog | |
In Vitro | Benzylimidazole 是一种选择性血栓素合成酶抑制剂和 UDP-葡萄糖醛基转移酶刺激剂。血栓素合成酶是一种细胞色素 P450 酶。细胞色素 P450 蛋白参与催化药物代谢和胆固醇、类固醇和其他脂类合成的许多反应。该酶在一些病理生理过程中起重要作用,包括止血、心血管疾病和中风。该基因表达两种转录变体。1-苯并咪唑选择性抑制血栓博烷合成酶活性。1-苯并咪唑降低大鼠脑缺血再灌注损伤后 TXB2 水平,增加血流量。雄性 Wistar 大鼠经胃给予 1-苯并咪唑 (25、75和100 mg/kg/天) 可引起剂量依赖性肝炎。1-苯并咪唑降低血浆甘油三酯水平 60-70%。1-苯并咪唑刺激三种不同形式的 UDP-葡萄糖醛基转移酶。1-苯并咪唑对 4-甲基菊酮、1-萘酚、吗啡和一种单萜类醇 nopol 的活性显著提高。苯并咪唑呈浓度依赖性增加肝细胞 CYP1A 催化活性和 CYP1A mRNA。 |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 310.0±11.0 °C at 760 mmHg |
Melting Point | 68-70 °C(lit.) |
Molecular Formula | C10H10N2 |
Molecular Weight | 158.20 |
Flash Point | 141.3±19.3 °C |
Exact Mass | 158.084396 |
PSA | 17.82000 |
LogP | 1.46 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.580 |
Water Solubility | insoluble |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933290090 |
Precursor 9 | |
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DownStream 9 | |
HS Code | 2933290090 |
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Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |