86443-19-8

86443-19-8 structure

Name: 1,4-DPCA ethyl ester
Chemical Name: 4-oxo-1,4-dihydro-[1,10]phenanthroline-3-carboxylic acid ethyl ester
CAS Number: 86443-19-8
Molecular Formula: C₁₅H₁₂N₂O₃
Molecular Weight: 268.26700
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
Create Date: 2016-04-30 08:52:19
Modify Date: 2024-01-29 17:50:50
1,4-DPCA ethyl ester is the ethyl ester of 1,4-DPCA and can inhibit factor inhibiting HIF (FIH)[1].

Name	4-oxo-1,4-dihydro-[1,10]phenanthroline-3-carboxylic acid ethyl ester
Synonyms	ethyl 1-benzyl-4-oxonipecotate ethyl N-benzyl-4-oxo--3-piperidinecarboxylate ethyl 4-oxo-1-benzylpiperidine-3-carboxylate ethyl 1,4-dihydro-4-oxo-1,10-phenanthroline-3-carboxylate 1-Benzyl-3-ethoxycarbonyl-4-piperidone ethyl-N-benzyl-4-oxo-piperidinecarboxylate ethyl1-benzyl-4-oxopiperidine-3-carboxylate 1-Benzyl-3-carboethoxy-4-piperidone ethyl 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylate 1-Benzyl-3-carbethoxy-4-piperidone

Description	1,4-DPCA ethyl ester is the ethyl ester of 1,4-DPCA and can inhibit factor inhibiting HIF (FIH)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase
In Vitro	1,4-DPCA ethyl ester is a tricyclic compound that inhibits factor inhibiting HIF (FIH)[1].
References	[1]. Biswadip Banerji, et al. The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids. Chem Commun (Camb). 2005 Nov 21;(43):5438-40.

Molecular Formula	C₁₅H₁₂N₂O₃
Molecular Weight	268.26700
Exact Mass	268.08500
PSA	72.05000
LogP	2.25300

130728-49-3

~82%

86443-19-8

Literature: Banerji, Biswadip; Conejo-Garcia, Ana; McNeill, Luke A.; McDonough, Michael A.; Buck, Matthew R. G.; Hewitson, Kirsty S.; Oldham, Neil J.; Schofield, Christopher J. Chemical Communications, 2005 , # 43 p. 5438 - 5440

578-66-5

86443-19-8

87-13-8

86443-19-8

Literature: Snyder; Freier Journal of the American Chemical Society, 1946 , vol. 68, p. 1320 Full Text View citing articles Show Details Lappin Journal of Chemical Education, 1951 , vol. 28, p. 126 Full Text View citing articles Show Details Shivalkar; Sunthankar Journal of Scientific and Industrial Research, 1959 , vol. 18 B, p. 447

Precursor 2
578-66-5 87-13-8
DownStream 2
1891-14-1 53946-49-9

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