Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Abz-FRK（Dnp）-P TFA
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Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Autocamtide-2-related inhibitory peptide
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Taiwan Oyi peptide Co. Ltd
China
Product Name: Autocamtide-2-Related Inhibitory Peptide trifluoroacetate salt
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

167114-91-2

167114-91-2 structure

167114-91-2 structure

Name: Autocamtide-2-Related Inhibitory Peptide trifluoroacetate salt
Chemical Name: Autocamtide 2-related inhibitory peptide
CAS Number: 167114-91-2
Molecular Formula: C₆₄H₁₁₆N₂₂O₁₉
Molecular Weight: 1822.12000
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2018-12-23 12:44:30
Modify Date: 2024-01-05 13:55:39
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

Name	Autocamtide 2-related inhibitory peptide
Synonyms	AIP [Ala9]-Autocamtide 2 Autocamtide-2-related inhibitory peptide

Description	Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> CaMK Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Neurological Disease
Target	IC50: 40 nM (CaMKII)[1].
In Vitro	It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].
References	[1]. Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12.

Molecular Formula	C₆₄H₁₁₆N₂₂O₁₉
Molecular Weight	1822.12000
Exact Mass	1821.07000
PSA	746.43000
LogP	8.46970

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22-36
Safety Phrases	22-24/25-26
RIDADR	NONH for all modes of transport