109028-10-6

109028-10-6 structure

Name: CGS 12066B dimaleate
Chemical Name: 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate
CAS Number: 109028-10-6
Molecular Formula: C₂₅H₂₅F₃N₄O₈
Molecular Weight: 566.48300
Create Date: 2017-07-29 19:55:47
Modify Date: 2024-03-03 17:04:16
CGS 12066 (dimaleate) dimaleate is a selective 5-HT1B receptor agonist with an IC50 of 51 nM[1].

Name	4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate
Synonyms	c-JUN peptide CGS 12066B dimaleate,7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxalinedimaleate

Description	CGS 12066 (dimaleate) dimaleate is a selective 5-HT1B receptor agonist with an IC50 of 51 nM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1B Receptor:51 nM (IC50)
References	[1]. Neale RF, et al. Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist. Eur J Pharmacol. 1987 Apr 7;136(1):1-9.