84468-24-6
84468-24-6 structure
- Name: HA-100
- Chemical Name: 5-piperazin-1-ylsulfonylisoquinoline
- CAS Number: 84468-24-6
- Molecular Formula: C13H15N3O2S
- Molecular Weight: 277.34200
- Catalog: Signaling Pathways Cytoskeleton Myosin
- Create Date: 2018-12-03 16:21:38
- Modify Date: 2024-01-11 14:03:08
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HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), Protein kinase C (PKC) and MLC-kinase with IC50s of 4, 8, 12 and 240 μM, respectively.
| Name | 5-piperazin-1-ylsulfonylisoquinoline |
|---|---|
| Synonyms |
Tocris-0543
ha-100 MFCD01310980 |
| Description | HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), Protein kinase C (PKC) and MLC-kinase with IC50s of 4, 8, 12 and 240 μM, respectively. |
|---|---|
| Related Catalog | |
| Target |
PKC:12 μM (IC50) PKG:4 μM (IC50) PKA:8 μM (IC50) MLCK:240 μM (IC50) |
| References |
| Density | 1.332g/cm3 |
|---|---|
| Boiling Point | 497.4ºC at 760 mmHg |
| Molecular Formula | C13H15N3O2S |
| Molecular Weight | 277.34200 |
| Flash Point | 254.6ºC |
| Exact Mass | 277.08800 |
| PSA | 70.68000 |
| LogP | 2.17620 |
| Index of Refraction | 1.639 |
| Storage condition | −20°C |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| RTECS | TM0862600 |
| HS Code | 2935009090 |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |