34823-86-4
34823-86-4 structure
- Name: GTP 14564
- Chemical Name: 3-phenyl-1H-[1]benzofuro[3,2-c]pyrazole
- CAS Number: 34823-86-4
- Molecular Formula: C15H10N2O
- Molecular Weight: 234.25
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
- Create Date: 2016-11-20 16:15:36
- Modify Date: 2024-01-06 11:40:02
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GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells[1].
| Name | 3-phenyl-1H-[1]benzofuro[3,2-c]pyrazole |
|---|---|
| Synonyms | 3-Phenyl-1H-benzofuro<3,2-c>pyrazol |
| Description | GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells[1]. |
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| Related Catalog | |
| References |
| Density | 1.321g/cm3 |
|---|---|
| Boiling Point | 459.1ºC at 760mmHg |
| Molecular Formula | C15H10N2O |
| Molecular Weight | 234.25 |
| Flash Point | 240.7ºC |
| Exact Mass | 234.07900 |
| PSA | 41.82000 |
| LogP | 3.97610 |
| Index of Refraction | 1.738 |
| HS Code | 2934999090 |
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|
~86%
34823-86-4 |
| Literature: Sales, Zachary S.; Mani, Neelakandha S. Journal of Organic Chemistry, 2009 , vol. 74, # 2 p. 891 - 894 |
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~98%
34823-86-4 |
| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
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~11%
34823-86-4 |
| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
|
~92%
34823-86-4 |
| Literature: Zhou, Zhong-Zhen; Zou, Min; Zhou, Jia; Zhou, Chun-Qiong; Deng, Yan-Hong; Chen, Ming-Hui; Gu, Chun-Ping; Jiang, Zhi-Hong; Chen, Wen-Hua; Liu, Shu-Wen Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 8 p. 1057 - 1061 |
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~%
34823-86-4 |
| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
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~%
34823-86-4 |
| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
|
~%
34823-86-4 |
| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
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34823-86-4 |
| Literature: Mosher,W.A. et al. Journal of Organic Chemistry, 1972 , vol. 37, p. 2402 - 2405 |
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Detail
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| Literature: Gatta; Settimj Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 937 - 943 |
| Precursor 5 | |
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| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |