52727-57-8

52727-57-8 structure

Name: Methyl 2-amino-5-bromobenzoate
Chemical Name: methyl 2-amino-5-bromobenzoate
CAS Number: 52727-57-8
Molecular Formula: C₈H₈BrNO₂
Molecular Weight: 230.06
Catalog: Chemical reagent Organic reagent Ester Methyl ester compound
Create Date: 2018-04-25 08:00:00
Modify Date: 2024-01-02 17:29:55
Methyl 2-amino-5-bromobenzoate (compound 8/12) can be used for synthesis of 2-benzamidobenzoic acids, which are known FabH inhibitors. The derivates also inhibit PqsD, the pqs quorum sensing (QS) system of Pseudomonas aeruginosa, involving the production of a number of virulence factors and biofilm formation[1].

Name	methyl 2-amino-5-bromobenzoate
Synonyms	estere metilico dell'acido 5-bromoantranilico Methyl 2-amino-5-bromobenzoate Benzoic acid, 2-amino-5-bromo-, methyl ester Benzoic acid,2-amino-5-bromo-,methyl ester,hydrochloride MFCD00144761 Methyl-2-amino-5-brombenzolcarboxylat 2-Amino-5-bromobenzoic Acid Methyl Ester methyl 2-amino-5-bromo-benzoate 5-Bromoanthranilic Acid Methyl Ester Methyl 5-Bromoanthranilate 5-bromo-2-amino-benzoic acid methyl ester METHYL2-AMINO-5-BROMOBENZOATE

Description	Methyl 2-amino-5-bromobenzoate (compound 8/12) can be used for synthesis of 2-benzamidobenzoic acids, which are known FabH inhibitors. The derivates also inhibit PqsD, the pqs quorum sensing (QS) system of Pseudomonas aeruginosa, involving the production of a number of virulence factors and biofilm formation[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Weidel E, et al. Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking. J Med Chem. 2013 Aug 8;56(15):6146-55.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%