Name | sis3 |
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Synonyms |
(2E)-1-(6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one hydrochloride (1:1)
2-Propen-1-one, 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-, (2E)-, hydrochloride (1:1) |
Description | SIS3 is a cell-permeable and selective inhibitor of Smad3. It inhibits Smad3 phosphorylation with an IC50 of 3 µM. |
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Related Catalog | |
References |
Boiling Point | 737.2ºC at 760 mmHg |
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Molecular Formula | C28H28ClN3O3 |
Molecular Weight | 489.993 |
Flash Point | 399.7ºC |
Exact Mass | 489.181915 |
PSA | 56.59000 |
LogP | 5.59550 |
Storage condition | -20℃ |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |