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152-53-4

152-53-4 structure
152-53-4 structure
  • Name: Cycloguanil Hydrochloride
  • Chemical Name: 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine,hydrochloride
  • CAS Number: 152-53-4
  • Molecular Formula: C11H15Cl2N5
  • Molecular Weight: 288.17600
  • Catalog: Signaling Pathways Anti-infection Parasite
  • Create Date: 2018-12-20 15:20:40
  • Modify Date: 2024-01-03 08:15:51
  • Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
Name 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine,hydrochloride
Synonyms 1-(4-chloro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diyldiamine,hydrochloride
4,6-diamino-1-(4'-chlorophenyl)-1,2-dihydro-2,2-dimethyl-1,3,5-triazine
CYCLOGUANIL HYDROCHLORIDE
BN 2410
Chloroguanide triazine hydrochloride
1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride
1-(4-CHLOROPHENYL)-4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1,3,5-TRIAZINE HCL
1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride
1-(4'-chlorophenyl)-2,2-dimethyl-4,6-diamino-1,2-dihydro-1,3,5-triazine hydrochloride
1-(4-Chlor-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,5]triazin-2,4-diyldiamin,Hydrochlorid
Boiling Point 400.7ºC at 760mmHg
Melting Point 210-215ºC
Molecular Formula C11H15Cl2N5
Molecular Weight 288.17600
Flash Point 196.1ºC
Exact Mass 287.07000
PSA 80.00000
LogP 2.66430
Vapour Pressure 1.25E-06mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU2625000
CHEMICAL NAME :
Cycloguanil hydrochloride
CAS REGISTRY NUMBER :
152-53-4
LAST UPDATED :
199106
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H14-Cl-N5.Cl-H
MOLECULAR WEIGHT :
288.21
WISWESSER LINE NOTATION :
T6N CN EN BHJ AR DG& B1 B1 DZ FZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
54 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,487,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATMPA2 Annals of Tropical Medicine and Parasitology. (Grune & Stratton, Inc., POB 6280, Duluth, MN 55806) V.1- 1907- Volume(issue)/page/year: 74,393,1980
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
24 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,487,1971
Hazard Codes Xi

Chemsrc provides CAS#:152-53-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 152-53-4 | Chemsrc address: https://www.chemsrc.com/en/baike/1107224.html

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