Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ValerylSalicylate
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Purity: 98.0%
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64206-54-8

64206-54-8 structure

64206-54-8 structure

Name: valerylsalicylic acid
Chemical Name: valerylsalicylic acid
CAS Number: 64206-54-8
Molecular Formula: C₁₂H₁₄O₄
Molecular Weight: 222.24
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2018-03-13 08:00:00
Modify Date: 2024-01-14 17:35:15
Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1].

Name	valerylsalicylic acid
Synonyms	valerylsalicylic acid 2-Valeryloxybenzoic acid Valerylsalicylic acid vsa 2-pentanoyloxybenzoic acid Benzoic acid, 2-[(1-oxopentyl)oxy]- 2-(Pentanoyloxy)benzoic acid MFCD00041466

Description	Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1
References	[1]. Siqueira-Junior JM, et al. Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice. Pharmacol Res. 2003 Nov;48(5):437-43.

Density	1.2±0.1 g/cm3
Boiling Point	357.6±25.0 °C at 760 mmHg
Melting Point	86-87ºC(lit.)
Molecular Formula	C₁₂H₁₄O₄
Molecular Weight	222.24
Flash Point	135.5±16.7 °C
Exact Mass	222.089203
PSA	63.60000
LogP	2.78
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.530

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO6840000

CHEMICAL NAME :: Salicylic acid, valerate

CAS REGISTRY NUMBER :: 64206-54-8

BEILSTEIN REFERENCE NO. :: 3292055

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H14-O4

MOLECULAR WEIGHT :: 222.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 2,229,1979

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
HS Code	2918990090

2082-59-9 structure

2082-59-9

69-72-7 structure

69-72-7

~%

64206-54-8 structure

64206-54-8

Literature: Hofstee Journal of Biological Chemistry, 1952 , vol. 199, p. 365,366

Precursor 2
2082-59-9 69-72-7
DownStream 0

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%