2784-50-1
2784-50-1 structure
- Name: L-Glutamic acid-d5
- Chemical Name: (2S)-2-amino-2,3,3,4,4-pentadeuteriopentanedioic acid
- CAS Number: 2784-50-1
- Molecular Formula: C5H4D5NO4
- Molecular Weight: 152.160
- Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
- Create Date: 2018-03-15 08:00:00
- Modify Date: 2024-01-07 20:08:49
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L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
| Name | (2S)-2-amino-2,3,3,4,4-pentadeuteriopentanedioic acid |
|---|---|
| Synonyms |
L-(2,3,3,4,4-H)Glutamic acid
glutamic acid-d5 2,3,3,4,4-pentadeuterio-L-glutamic acid Glusate-d5 L-Glutamic-2,3,3,4,4-d acid L-glutamic-2,3,3,4,4-d5 acid Glutacid-d5 Glutamicol-d5 L-|A-Aminoglutaric Acid-d5 Glutaminol-d5 Glutaton-d5 Glutamidex-d5 |
| Description | L-Glutamic acid-d5 is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 333.8±32.0 °C at 760 mmHg |
| Melting Point | 205ºC (dec.)(lit.) |
| Molecular Formula | C5H4D5NO4 |
| Molecular Weight | 152.160 |
| Flash Point | 155.7±25.1 °C |
| Exact Mass | 152.084549 |
| PSA | 100.62000 |
| LogP | -1.43 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.522 |
| Storage condition | -20°C |
| WGK Germany | 3 |
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