663620-70-0
663620-70-0 structure
- Name: rac-AZD 6482
- Chemical Name: 2-({1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin -9-yl]ethyl}amino)benzoic acid
- CAS Number: 663620-70-0
- Molecular Formula: C22H24N4O4
- Molecular Weight: 408.45000
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2017-03-19 23:16:52
- Modify Date: 2024-07-18 12:56:10
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rac-AZD 6482 (rac-KIN-193) is a less active racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
| Name | 2-({1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin -9-yl]ethyl}amino)benzoic acid |
|---|---|
| Synonyms |
(+/-)-1-tert-Butyldimethylsilyloxy-3-vinylcyclohex-2-ene
2-{[1-(7-methyl-2-morpholin-4-yl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino}benzoic acid 3-<(tert-Butyldimethylsilyl)oxy>-1-vinylcyclohexene Silane,(1,1-dimethylethyl)[(3-ethenyl-2-cyclohexen-1-yl)oxy]dimethyl (+/-)-2-({1-[7-methyl-2-(morpholin-4-yl)-4-oxo-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid 3-(tert-butyldimethylsiloxy)-1-vinyl-1-cyclohexene |
| Description | rac-AZD 6482 (rac-KIN-193) is a less active racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C22H24N4O4 |
|---|---|
| Molecular Weight | 408.45000 |
| Exact Mass | 408.18000 |
| PSA | 96.17000 |
| LogP | 2.84880 |
|
~67%
663620-70-0 |
| Literature: Fjellstrom, Ola; Gustafsson, David; Lindberg, Jan A.; Jackson, Shaun Patent: US2009/191177 A1, 2009 ; Location in patent: Page/Page column 7 ; US 20090191177 A1 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |