132928-46-2

132928-46-2 structure

Name: PF-10040
Chemical Name: 1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline,hydrochloride
CAS Number: 132928-46-2
Molecular Formula: C₂₀H₂₄ClNO₂
Molecular Weight: 345.86300
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-04-16 07:53:39
Modify Date: 2024-02-04 18:04:17
PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].

Name	1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline,hydrochloride
Synonyms	1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline hydrochloride 1-(2-(3,4-Dimethoxyphenyl)ethyl)-3,4-dihydro-6-methylisoquinoline hydrochloride Isoquinoline,1-(2-(3,4-dimethoxyphenyl)ethyl)-3,4-dihydro-6-methyl-,hydrochloride 1-(3,4-Dimethoxyphenylethyl)-6-methyl-3,4-dihydroisoquinoline

Description	PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Herd CM, et, al. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. Br J Pharmacol. 1994 Jan;111(1):7-12. [2]. Wallace JL, et, al. Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF. J Lipid Mediat. 1993 Jun;7(2):183-96.