PF-10040

Modify Date: 2024-02-04 18:04:17

PF-10040 Structure
PF-10040 structure
Common Name PF-10040
CAS Number 132928-46-2 Molecular Weight 345.86300
Density N/A Boiling Point 446.3ºC at 760mmHg
Molecular Formula C20H24ClNO2 Melting Point N/A
MSDS N/A Flash Point 179.9ºC

 Use of PF-10040


PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].

 Names

Name 1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline,hydrochloride
Synonym More Synonyms

 PF-10040 Biological Activity

Description PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis[1][2].
Related Catalog
References

[1]. Herd CM, et, al. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. Br J Pharmacol. 1994 Jan;111(1):7-12.  

[2]. Wallace JL, et, al. Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF. J Lipid Mediat. 1993 Jun;7(2):183-96.  

 Chemical & Physical Properties

Boiling Point 446.3ºC at 760mmHg
Molecular Formula C20H24ClNO2
Molecular Weight 345.86300
Flash Point 179.9ºC
Exact Mass 345.15000
PSA 30.82000
LogP 4.22780
Vapour Pressure 9.68E-08mmHg at 25°C

 Synonyms

1-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-3,4-dihydroisoquinoline hydrochloride
1-(2-(3,4-Dimethoxyphenyl)ethyl)-3,4-dihydro-6-methylisoquinoline hydrochloride
Isoquinoline,1-(2-(3,4-dimethoxyphenyl)ethyl)-3,4-dihydro-6-methyl-,hydrochloride
1-(3,4-Dimethoxyphenylethyl)-6-methyl-3,4-dihydroisoquinoline
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