1255507-88-0

1255507-88-0 structure
1255507-88-0 structure

Name trideuteriomethyl N-(1H-benzimidazol-2-yl)carbamate
Synonyms Carbendazim-d3
Methyl-d3 2-benzimidazolecarbamate
Description Carbendazimb-d3 is the deuterium labeled Ofloxacin. Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula C9H6D3N3O2
Molecular Weight 194.21
Exact Mass 194.08800
PSA 67.01000
LogP 1.81420
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Danger
Hazard Statements H340-H360FD-H410
Precautionary Statements P201-P273-P308 + P313-P501
Hazard Codes T,N
Risk Phrases 46-60-61-50/53
Safety Phrases 53-45-60-61
RIDADR UN 3077 9 / PGIII