Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Chloro-5-(trifluoromethyl)pyridine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Chloro-5-(trifluoromethyl)pyridine
Price: ￥238.0/100g ￥88.0/25g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Chloro-5-trifluoromethylpyridine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Chloro-5-trifluoromethylpyridine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

52334-81-3

52334-81-3 structure

Name: 2-Chloro-5-(trifluoromethyl)pyridine
Chemical Name: 2-Chloro-5-trifluoromethylpyridine
CAS Number: 52334-81-3
Molecular Formula: C₆H₃ClF₃N
Molecular Weight: 181.543
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Methylpyridine
Create Date: 2018-05-27 08:00:00
Modify Date: 2024-01-02 11:37:07

Name	2-Chloro-5-trifluoromethylpyridine
Synonyms	2-Chloro-5-Trifluoromethylpyridine EINECS 257-856-5 Pyridine, 2-chloro-5-(trifluoromethyl)- 2-Chloro-5-(trifluoromethyl)pyridine T6NJ BG EXFFF MFCD00042225

Density	1.4±0.1 g/cm3
Boiling Point	171.6±35.0 °C at 760 mmHg
Melting Point	32-34 °C(lit.)
Molecular Formula	C₆H₃ClF₃N
Molecular Weight	181.543
Flash Point	57.6±25.9 °C
Exact Mass	180.990616
PSA	12.89000
LogP	2.44
Vapour Pressure	1.8±0.3 mmHg at 25°C
Index of Refraction	1.447
Storage condition	0-6°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7530000

CHEMICAL NAME :: Pyridine, 2-chloro-5-(trifluoromethyl)-

CAS REGISTRY NUMBER :: 52334-81-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H3-Cl-F3-N

MOLECULAR WEIGHT :: 181.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/m3/6H/4W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5500 mg/kg/21D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 800 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,57,1993

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S26-S37/39-S36/37/39
RIDADR	2811
WGK Germany	3
RTECS	US7530000
Packaging Group	III
Hazard Class	6.1
HS Code	2933399090

22253-72-1

~25%

52334-81-3

65753-47-1

Literature: US2012/259125 A1, ; Page/Page column 3 ;

33252-63-0

52334-81-3

Literature: US4249009 A1, ;

69045-78-9

~53%

52334-81-3

Literature: Heterocycles, , vol. 22, # 1 p. 117 - 124

2926-29-6

444120-91-6

~83%

52334-81-3

Literature: Organic Letters, , vol. 14, # 19 p. 4979 - 4981,3 Organic Letters, , vol. 14, # 19 p. 4979 - 4981

69045-79-0

120120-26-5

~71%

52334-81-3

Literature: Chemical Communications, , # 14 p. 1909 - 1911

7783-56-4

69045-78-9

52334-81-3

Literature: US4152328 A1, ;

69045-79-0

2923-18-4

~86%

20857-44-7

52334-81-3

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 921 - 926

69045-78-9

52334-81-3

69045-82-5

Literature: European Journal of Medicinal Chemistry, , vol. 24, # 3 p. 249 - 258

Precursor 9
22253-72-1 33252-63-0 69045-78-9 2926-29-6
444120-91-6 69045-79-0 120120-26-5 7783-56-4
2923-18-4
DownStream 10
33252-63-0 605680-62-4 306934-70-3 142946-80-3
147541-04-6 505084-59-3 937602-15-8 50488-42-1
505084-55-9 505084-56-0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

52334-81-3	261956-65-4
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934279-60-4	536693-96-6
505084-57-1	1260782-19-1
1158522-08-7	940364-43-2
1697699-56-1	134104-43-1
131615-57-1	6906-52-1
930439-75-1	1697431-75-6
1018584-77-4	1375289-11-4