61093-23-0

61093-23-0 structure

Name: Cyclic-di-GMP
Chemical Name: c-di-GMP
CAS Number: 61093-23-0
Molecular Formula: C₂₀H₂₄N₁₀O₁₄P₂
Molecular Weight: 690.41100
Catalog: Signaling Pathways Immunology/Inflammation STING
Create Date: 2016-12-06 04:25:00
Modify Date: 2024-01-07 16:44:04
Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.

Name	c-di-GMP
Synonyms	Cyclic diguanylate cyclic di-GMP 3',5'-Cyclic diguanylic acid Cyclic-di-GMP

Description	Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> STING Research Areas >> Cancer
Target	STING[1]
References	[1]. Nakamura T, et al. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. J Control Release. 2015 Oct 28;216:149-57. [2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.