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874208-91-0

874208-91-0 structure
874208-91-0 structure
  • Name: m-PEG6-CH2CH2COOH
  • Chemical Name: 3-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionic acid
  • CAS Number: 874208-91-0
  • Molecular Formula: C16H32O9
  • Molecular Weight: 368.42000
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-03-21 19:57:33
  • Modify Date: 2024-01-14 13:11:06
  • m-PEG6-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

Name 3-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionic acid
Synonyms 4,7,10,13,16,19,22-Heptaoxatricosanoic acid
Description m-PEG6-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. John F. Donovan, et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.

Molecular Formula C16H32O9
Molecular Weight 368.42000
Exact Mass 368.20500
PSA 101.91000
LogP 0.20710