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1120-02-1

1120-02-1 structure
1120-02-1 structure

Name Stearyltrimethylammonium Bromide
Synonyms Octadecy trimethyl ammonium bromide
trimethyl(octadecyl)azanium,bromide
EINECS 214-294-5
Trimethyloctadecylammonium bromide
Octadecyltrimethylammonium bromide
1-Octadecanaminium, N,N,N-trimethyl-, bromide
1-Octadecanaminium, N,N,N-trimethyl-, bromide (1:1)
N,N,N-Trimethyloctadecan-1-aminium bromide
N,N,N-Trimethyl-1-octadecanaminium bromide
MFCD00043171
Trimethylstearylammonium Bromide
Description Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus[1][2].
Related Catalog
Target

IC50: 1.9 μM (Dynamin I)[1]

In Vitro Trimethyloctadecylammonium bromide (1 μM-100 μM; 10 min) inhibits EGF-A488 endocytosis in COS-7 cells, with an IC50 value of 16 μM[1]. Trimethyloctadecylammonium bromide (30 μM; 10 min; 37 ℃) shows no effect on EGFR activation in A431 cells with insignificant EGFR autophosphorylation change[1]. Trimethyloctadecylammonium bromide (stearyl-) (1 nM-1 mM) inhibits Staphylococcus aureus with of 59.5 nM (CKD assay) and 0.33 mM (CMC assay), respectively[2].
Melting Point ~250 °C (dec.)(lit.)
Molecular Formula C21H46BrN
Molecular Weight 392.501
Exact Mass 391.281342
LogP 3.95810
Stability Stable. Hygroscopic. Incompatible with strong oxidizing agents. Protect from moisture.
Water Solubility soluble
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2923900090

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1120-02-1 structure

1120-02-1

Literature: Journal of the American Chemical Society, , vol. 99, p. 4947 - 4954 Journal of Physical Chemistry, , vol. 88, # 21 p. 5093 - 5099
Precursor  2

DownStream  1

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%