Name | Stearyltrimethylammonium Bromide |
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Synonyms |
Octadecy trimethyl ammonium bromide
trimethyl(octadecyl)azanium,bromide EINECS 214-294-5 Trimethyloctadecylammonium bromide Octadecyltrimethylammonium bromide 1-Octadecanaminium, N,N,N-trimethyl-, bromide 1-Octadecanaminium, N,N,N-trimethyl-, bromide (1:1) N,N,N-Trimethyloctadecan-1-aminium bromide N,N,N-Trimethyl-1-octadecanaminium bromide MFCD00043171 Trimethylstearylammonium Bromide |
Description | Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus[1][2]. |
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Related Catalog | |
Target |
IC50: 1.9 μM (Dynamin I)[1] |
In Vitro | Trimethyloctadecylammonium bromide (1 μM-100 μM; 10 min) inhibits EGF-A488 endocytosis in COS-7 cells, with an IC50 value of 16 μM[1]. Trimethyloctadecylammonium bromide (30 μM; 10 min; 37 ℃) shows no effect on EGFR activation in A431 cells with insignificant EGFR autophosphorylation change[1]. Trimethyloctadecylammonium bromide (stearyl-) (1 nM-1 mM) inhibits Staphylococcus aureus with of 59.5 nM (CKD assay) and 0.33 mM (CMC assay), respectively[2]. |
Melting Point | ~250 °C (dec.)(lit.) |
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Molecular Formula | C21H46BrN |
Molecular Weight | 392.501 |
Exact Mass | 391.281342 |
LogP | 3.95810 |
Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. Protect from moisture. |
Water Solubility | soluble |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi:Irritant |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2923900090 |
~% 1120-02-1 |
Literature: Journal of the American Chemical Society, , vol. 99, p. 4947 - 4954 Journal of Physical Chemistry, , vol. 88, # 21 p. 5093 - 5099 |
Precursor 2 | |
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DownStream 1 | |
HS Code | 2923900090 |
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Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |