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24356-66-9

24356-66-9 structure
24356-66-9 structure
  • Name: Vidarabine monohydrate
  • Chemical Name: 9-beta-D-arabinofuranosyl-9H-purine-6-amine monohydrate
  • CAS Number: 24356-66-9
  • Molecular Formula: C10H15N5O5
  • Molecular Weight: 285.257
  • Catalog: Signaling Pathways Anti-infection HSV
  • Create Date: 2018-02-25 08:00:00
  • Modify Date: 2024-01-02 18:05:28
  • Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral drug which is active against herpes simplex viruses (HSV) and varicella zoster viruses[1].

Name 9-beta-D-arabinofuranosyl-9H-purine-6-amine monohydrate
Synonyms adenine arabinoside
9H-purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate (1:1)
9-(β-D-Arabinofuranosyl)adenine Monohydrate
Arasena-A
7H-Purine-7-carboxylic acid,6-amino-,phenylmethyl ester
9b-D-Arabinofuranosyladenine Monohydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-amine hydrate
(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol hydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
spongoadenosine
9-(b-D-arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxyméthyl)tétrahydrofurane-3,4-diol hydrate
6-amino-purine-7-carboxylic acid benzyl ester
Vira ATM
Ara-A Monohydrate
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-aminhydrat
7-Carbobenzoxy-adenin
9-β-D-arabinofuranosyl-9H-purin-6-amine hydrate
Benzyl 6-aminopurin-7-carboxylat
Adenine 9-β-D-Arabinofuranoside Monohydrate
(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolhydrat
9b-D-Arabinofuranosyl-9H-purine-6-amine Monohydrate
arabinosyladenine
b-D-Arabinofuranosyladenine Monohydrate
Adenin-7-carbonsaeurebenzylester
9H-Purin-6-amine, 9-β-D-arabinofuranosyl-, hydrate (1:1)
Description Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral drug which is active against herpes simplex viruses (HSV) and varicella zoster viruses[1].
Related Catalog
References

[1]. Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.

Melting Point 257.0-257.5ºC (0.4 H2O)
Molecular Formula C10H15N5O5
Molecular Weight 285.257
Exact Mass 285.107330
PSA 148.77000

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU6210000
CHEMICAL NAME :
Adenine, 9-beta-D-arabinofuranosyl-, monohydrate
CAS REGISTRY NUMBER :
24356-66-9
LAST UPDATED :
199703
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H13-N5-O4.H2-O
MOLECULAR WEIGHT :
285.30
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ IZ D- ET5OTJ B1Q CQ DQ &QH *D-ARABINO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>7950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4677 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - peritonitis
REFERENCE :
AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2367 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 454 (estimated) No. of Female Employees: 230 (estimated)
Hazard Codes Xi
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%