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128322-44-1

128322-44-1 structure
128322-44-1 structure
  • Name: MCLA hydrochloride
  • Chemical Name: 2-Methyl-6-(4-Methoxyphenyl)-3,7-Dihydroimidazo[1,2-a]Pyrazin-3-One Hydrochloride
  • CAS Number: 128322-44-1
  • Molecular Formula: C14H14ClN3O2
  • Molecular Weight: 291.733
  • Catalog: Dye Reagents
  • Create Date: 2018-12-23 21:42:33
  • Modify Date: 2024-01-11 17:30:18
  • MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
Name 2-Methyl-6-(4-Methoxyphenyl)-3,7-Dihydroimidazo[1,2-a]Pyrazin-3-One Hydrochloride
Synonyms 2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride
6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride
6-(4-methoxyphenyl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one,hydrochloride
MFCD00144728
6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride (1:1)
Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-methoxyphenyl)-2-methyl-, hydrochloride (1:1)
6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride
6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride
MCLA hydrochloride
Description MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
Related Catalog
In Vitro The non-specific luminescence remains almost constant for 10 min after the addition of MCLA hydrochloride (MCLA) and is not significantly influenced by SOD. The MCLA hydrochloride method is, however, 4.5-times more sensitive than the CLA method[1].
Kinase Assay The standard reaction mixture contains 1×l0-7 M MCLA hydrochloride (MCLA), 5×10-5 M hypoxanthine, XOD (6.5 U), SOD (0.2 to 20 ng/mL) or none, and 50 mM Tris-HCl buffer containing 0.1 mM EDTA at pH 7.8, in a total volume of 3.0 mL. Chemiluminescence measurement is initiated by the addition of MCLA hydrochloride to the standard incubation mixture excluding XOD, continued for 4 min without additive and for an additional 4 min after the addition of XOD. Chemiluminescence is measured using a luminescence reader at 25°C[1].
References

[1]. Kimura H, et al. Highly sensitive and reliable chemiluminescence method for the assay of superoxide dismutase inhuman erythrocytes. FEBS Lett. 1988 Nov 7;239(2):347-50.
Boiling Point 410.3ºC at 760 mmHg
Molecular Formula C14H14ClN3O2
Molecular Weight 291.733
Flash Point 201.9ºC
Exact Mass 291.077454
PSA 59.39000
LogP 2.80860
Vapour Pressure 3.95E-07mmHg at 25°C
Storage condition 2~8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes F+
Safety Phrases S22
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2933990090
Precursor  2

DownStream  0

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 128322-44-1 | Chemsrc address: https://www.chemsrc.com/en/baike/1193021.html

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