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26645-35-2

26645-35-2 structure
26645-35-2 structure
  • Name: phallacidin
  • Chemical Name: phallacidin
  • CAS Number: 26645-35-2
  • Molecular Formula: C37H50N8O13S
  • Molecular Weight: 846.90400
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2018-06-13 17:44:14
  • Modify Date: 2024-01-05 17:57:56
  • Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. Phallacidin binds filamentous actin (F-actin) like phalloidin (Item No. 18039), but contains a carboxyl group for coupling reactions.

Name phallacidin
Synonyms Cyclo[L-Ala-L-Trp2(1)-4,5-dihydroxy-L-Leu-L-Val-[(3S)-3-hydroxy-D-Asp-]-L-Cys(1)-L-c4Hyp-]
Cyclo(Ala-2-Mercapto-Trp-4,5-Dihydroxy-Leu-Val-erythro-3-Hydroxy-D-Asp-Cys-cis-4-Hydroxy-Pro)
PHALLICIDIN
cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro
CYCLO[ALA-2-MERCAPTO-TRP-4,5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO]
PHALLACIDIN
MFCD00063359
Description Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. Phallacidin binds filamentous actin (F-actin) like phalloidin (Item No. 18039), but contains a carboxyl group for coupling reactions.
Related Catalog
Density 1.54 g/cm3
Boiling Point 1435.2ºC
Molecular Formula C37H50N8O13S
Molecular Weight 846.90400
Flash Point 821.8ºC
Exact Mass 846.32200
PSA 354.22000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.683
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GT8943000
CHEMICAL NAME :
cyclic(L-Alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy -L-leucyl-L-valyl-ery thro-3-hydroxy- D-alpha-aspartyl-L-cysteinyl-cis-4-hydroxy-L-prolyl) cyclic (2-6)-sulfide
CAS REGISTRY NUMBER :
26645-35-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C37-H50-N8-O13-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CRBCAI CRC Critical Reviews in Biochemistry. (CRC Press, Inc., 2000 Corporate Blvd., NW, Boca Raton, FL 33431) V.1- 1972- Volume(issue)/page/year: 5,185,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,2142,1972
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300-H310-H330
Precautionary Statements P260-P264-P280-P284-P302 + P350-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+: Very toxic;
Risk Phrases R26/27/28
Safety Phrases S22;S45;S36/S37/S39
RIDADR UN 1544
RTECS GT8943000
Hazard Class 6.1(a)