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1937-19-5

1937-19-5 structure
1937-19-5 structure
  • Name: Aminoguanidine hydrochloride
  • Chemical Name: Aminoguanidine hydrochloride
  • CAS Number: 1937-19-5
  • Molecular Formula: CH7ClN4
  • Molecular Weight: 110.546
  • Catalog: Organic raw materials Amino compound Amide compound
  • Create Date: 2018-07-14 08:42:25
  • Modify Date: 2024-01-02 11:07:51
  • Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy.

Name Aminoguanidine hydrochloride
Synonyms Aminoguanidine hydrochloride
AMINOGUANIDINE SALT
MFCD00039074
N1-aminoguanidine hydrochloride
Guanylhydrazine hydrochloride
aminoguanidinium chloride
Aminoguanidine hydrochoride
1-aminoguanidine hydrochloride
6-Hydroxydopamine hydrobromide
EINECS 217-707-7
D015 AMinoguanidine hydrochloride
GUANYLHYDRAZINEHCL
Aminoguanidine HCL
amino-guanidinhydrochloride
aminoguanidine monohydrochloride
Hydrazinecarboximidamide, hydrochloride (1:1)
Hydrazinecarboximidamide hydrochloride (1:1)
carbazamidine monohydrochloride
Aminoguanidine salts
GUANIDINE,AMINO-,MONOHYDROCHLORIDE
hydrazinecarboximidamide hydrochloride
Aminoguanidine (hydrochloride)
Description Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy.
Related Catalog
Boiling Point 261.4ºC at 760 mmHg
Melting Point 162-166 °C(lit.)
Molecular Formula CH7ClN4
Molecular Weight 110.546
Flash Point 111.9ºC
Exact Mass 110.035927
PSA 87.92000
LogP 1.03640
Vapour Pressure 0.0116mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ME8430000
CHEMICAL NAME :
Guanidine, amino-, hydrochloride
CAS REGISTRY NUMBER :
1937-19-5
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C-H6-N4.Cl-H
MOLECULAR WEIGHT :
110.57
WISWESSER LINE NOTATION :
ZMYZUM &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2984 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,251,1926
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ME8430000
HS Code 2928000090

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1937-19-5 structure

1937-19-5

Literature: Journal of Medicinal Chemistry, , vol. 49, # 26 p. 7897 - 7901

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1937-19-5 structure

1937-19-5

Literature: Gazzetta Chimica Italiana, , vol. 24 I, p. 453

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1937-19-5 structure

1937-19-5

Literature: Russian Journal of Applied Chemistry, , vol. 84, # 3 p. 400 - 406

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1937-19-5 structure

1937-19-5

Literature: Chemische Berichte, , vol. 44, p. 2713 Gazzetta Chimica Italiana, , vol. 24 I, p. 453
HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%