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9004-66-4

9004-66-4 structure
9004-66-4 structure
  • Name: Iron dextran
  • Chemical Name: Iron-dextran
  • CAS Number: 9004-66-4
  • Molecular Formula: H2O4S.Fe
  • Molecular Weight: 1347.364
  • Catalog: API Blood system medication Anti-anemia drug
  • Create Date: 2018-02-06 08:00:00
  • Modify Date: 2024-01-02 22:44:34
  • Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals[1][2].

Name Iron-dextran
Synonyms MFCD00081553
Ferric hydroxide dextran complex
Description Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals[1][2].
Related Catalog
In Vivo Iron dextran (FeDex, IP, 4 weeks, 300 μL of 10 mg) treatment does not increase NSR iron but causes iron-trapping in the tetinal vasculature[1]. Four weeks of IP FeDex injection in 2-month-old WT mice leads to iron accumulation in the RPE and rVECs, but did not increase NSR iron or induce photoreceptor degeneration[1]. Animal Model: Wild-type (WT) and RS-HepcKO mice[1]. Dosage: IP. Administration: 300 μL of 10 mg daily for 5 days each week for 2 or 4 weeks. Result: Markedly elevated iron levels in 2 and 4 weeks of FeDex-injection groups, by 365.4-fold and 405.4-fold, respectively, compared with PBS controls.
References

[1]. Wanting Shu, et al. Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4378-4387.

[2]. D. R. ZIMMERMAN, et al. INJECTABLE IRON-DEXTRAN AND SEVERAL ORAL IRON TREATMENTS FOR THE PREVENTION OF IRONDEFICIENCY ANEMIA OF BABY PIGS x. Journal of Animal Science, Volume 18, Issue 4, November 1959, Pages 1409–1415.

Molecular Formula H2O4S.Fe
Molecular Weight 1347.364
Exact Mass 1346.576050
Appearance solution
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H317-H350
Precautionary Statements P201-P280-P308 + P313
Hazard Codes Xn
Risk Phrases R40;R42/43
Safety Phrases S23;S26;S45;S36/S37/S39
RIDADR NONH for all modes of transport
WGK Germany -
RTECS NI2200000