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9003-98-9

9003-98-9 structure
9003-98-9 structure
  • Name: Deoxyribonuclease
  • Chemical Name: Deoxyribonuclease
  • CAS Number: 9003-98-9
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Biochemical Enzymes and coenzymes
  • Create Date: 2018-02-07 08:00:00
  • Modify Date: 2024-01-04 19:53:01
  • Deoxyribonuclease (DNase) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].

Name Deoxyribonuclease
Synonyms Alkaline DNase
Alkaline deoxyribonuclease
DNA depolymerase
DNA endonuclease
DNA nuclease
DNAase
DNase
Deoxyribonuclease A
Deoxyribonuclease I
Deoxyribonucleic phosphatase
Desoxyribonuclease
Dornase
Pancreatic deoxyribonuclease
Pancreatic dornase
Description Deoxyribonuclease (DNase) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].
Related Catalog
In Vivo Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass[1]. Animal Model: Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection[1] Dosage: 0.1 U per mouse Administration: Intravenous injection; 0.1 U; once daily for three days Result: Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest. Animal Model: Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours[1] Dosage: 0.1 U per mouse Administration: Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal Result: Significantly prolongated survival after tumour cell inoculation compared to the untreated group.
Density 100 g/mL at 20 °C
Appearance solution (clear, colorless) | white
Storage condition −20°C
Water Solubility Soluble in 0.15 M sodium chloride (5.0mg/L) clear.
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 23-24/25-22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS RF0750000