39445-21-1

39445-21-1 structure

Name: Elastase from porcine pancreas
Chemical Name: human neutrophil
CAS Number: 39445-21-1
Molecular Formula: C₂₀H₃₁N₄O₇Cl
Molecular Weight: 474.93574
Catalog: Food additive Enzyme
Create Date: 2018-07-19 09:49:44
Modify Date: 2024-01-02 16:52:52
Elastase from porcine pancreas is a single polypeptide chain of 240 amino acid residues. Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters[1][2][3].

Name	human neutrophil
Synonyms	MFCD00130998 EINECS 254-453-6

Description	Elastase from porcine pancreas is a single polypeptide chain of 240 amino acid residues. Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Elastase from porcine pancreas induces emphysema in hamsters[3].
References	[1]. Shotton DM, et, al. Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6. [2]. Teshima T, et, al. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates. J Biol Chem. 1982 May 10;257(9):5085-91. [3]. Stone PJ, et, al. Induction and exacerbation of emphysema in hamsters with human neutrophil elastase inactivated reversibly by a peptide boronic acid. Am Rev Respir Dis. 1990 Jan;141(1):47-52.

Symbol	GHS07, GHS08
Signal Word	Danger, Warning
Hazard Statements	H315-H319-H334-H335
Precautionary Statements	P261-P280-P284-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn
Risk Phrases	R42;R36/37/38
Safety Phrases	S22;S24;S26;S36/S37
RIDADR	NONH for all modes of transport
WGK Germany	3