Name | (Dab7)-Leiurotoxin I |
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Description | Lei-Dab7 is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 increases theta-burst responses and increases LTP in rat hippocampal slices in vitro. |
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Related Catalog |
Molecular Formula | C141H236N46O39S6 |
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Molecular Weight | 3394.07 |