1026493-77-5
1026493-77-5 structure
- Name: Ack1 inhibitor 37
- Chemical Name: N-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- CAS Number: 1026493-77-5
- Molecular Formula: C28H31N5OS2
- Molecular Weight: 517.70900
- Create Date: 2018-04-30 09:44:54
- Modify Date: 2024-01-16 22:19:41
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Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM).
| Name | N-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
|---|
| Molecular Formula | C28H31N5OS2 |
|---|---|
| Molecular Weight | 517.70900 |
| Exact Mass | 517.19700 |
| PSA | 116.67000 |
| LogP | 5.99540 |