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1026493-77-5

1026493-77-5 structure
1026493-77-5 structure
  • Name: Ack1 inhibitor 37
  • Chemical Name: N-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • CAS Number: 1026493-77-5
  • Molecular Formula: C28H31N5OS2
  • Molecular Weight: 517.70900
  • Create Date: 2018-04-30 09:44:54
  • Modify Date: 2024-01-16 22:19:41
  • Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM).

Name N-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Molecular Formula C28H31N5OS2
Molecular Weight 517.70900
Exact Mass 517.19700
PSA 116.67000
LogP 5.99540