Ack1 inhibitor 37 structure
|
Common Name | Ack1 inhibitor 37 | ||
---|---|---|---|---|
CAS Number | 1026493-77-5 | Molecular Weight | 517.70900 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C28H31N5OS2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Ack1 inhibitor 37Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM). |
Name | N-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
---|
Molecular Formula | C28H31N5OS2 |
---|---|
Molecular Weight | 517.70900 |
Exact Mass | 517.19700 |
PSA | 116.67000 |
LogP | 5.99540 |