1215085-93-0

1215085-93-0 structure

Name: GLPG0492 (R enantiomer)
Chemical Name: (R)-(+)-4-[2,5-dioxo-4-(hydroxymethyl)-3-methyl-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
CAS Number: 1215085-93-0
Molecular Formula: C₁₉H₁₄F₃N₃O₃
Molecular Weight: 389.32800
Catalog: Research Areas Others
Create Date: 2018-06-23 10:55:17
Modify Date: 2024-01-07 22:24:50
GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator.

Name	(R)-(+)-4-[2,5-dioxo-4-(hydroxymethyl)-3-methyl-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Synonyms	(R)-4-[2,5-dioxo-4-hydroxymethyl-3-methyl-4-phenylimidazolidin-1-yl]-2-trifluoromethylbenzonitrile GLPG0492 (R enantiomer)

Description	GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator.
Related Catalog	Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Others
References	[1]. Nique F, et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. J Med Chem. 2012 Oct 11;55(19):8236-47. [2]. Cozzoli A, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24. [3]. Blanqué R, et al. Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization. BMC Musculoskelet Disord. 2014 Sep 3;15:291.