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116-43-8

116-43-8 structure
116-43-8 structure

Name 4'-(2-Thiazolylsulfamoyl)succinanilic acid
Synonyms EINECS 204-141-0
Succinanilic acid, 4'-(2-thiazolylsulfamoyl)-
MFCD00022437
succinylsulfathiazole
4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide Hydrate
Succinylsulfathiazole Hydrate
Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide
N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
N4-Succinyl-N-(2-thiazolyl)sulfanilamide Hydrate
N4-Succinyl-N-(2-thiazolyl)sulfanilamide
4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid
p-2-Thiazolylsulfamoylsuccinanilic acid
4-Oxo-4-{[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]amino}butanoic acid
4-oxo-4-{4-[(1,3-thiazol-2-ylamino)sulfonyl]anilino}butanoic acid
Description Succinylsulfathiazole is a sulfonamide, it is an ultra long acting drug.
Related Catalog
Density 1.6±0.1 g/cm3
Melting Point 187 - 193ºC
Molecular Formula C13H13N3O5S2
Molecular Weight 355.389
Exact Mass 355.029663
PSA 162.08000
LogP 0.68
Index of Refraction 1.679

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM4767000
CHEMICAL NAME :
Succinanilic acid, 4'-(2-thiazolylsulfamoyl)-
CAS REGISTRY NUMBER :
116-43-8
BEILSTEIN REFERENCE NO. :
0349989
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H13-N3-O5-S2
MOLECULAR WEIGHT :
355.41
WISWESSER LINE NOTATION :
T5N CSJ BMSWR DMV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,231,1942
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 7,151,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81640 No. of Facilities: 58 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 230 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R42/43
Safety Phrases S22-S36/37-S45
RIDADR 3249
WGK Germany 3
RTECS WM4767000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2935009090

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116-43-8 structure

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Literature: Burdulene; Stumbryavichyute; Talaikite; Vladyko; Boreko; Korobchenko Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 9 p. 471 - 473

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116-43-8 structure

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Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574 Journal of the Chemical Society, , p. 751

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116-43-8 structure

116-43-8

Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574

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116-43-8 structure

116-43-8

Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574

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116-43-8 structure

116-43-8

Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574
HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%