1421373-62-7
1421373-62-7 structure
- Name: Mutant EGFR inhibitor
- Chemical Name: N-(5-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide
- CAS Number: 1421373-62-7
- Molecular Formula: C27H30ClN7O2
- Molecular Weight: 520.02600
- Catalog: Research Areas Cancer
- Create Date: 2018-01-25 13:15:45
- Modify Date: 2024-08-24 19:00:43
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Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M.
| Name | N-(5-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide |
|---|---|
| Synonyms |
N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-(2-dimethylaminoethylmethylamino)-4-methoxyphenyl]prop-2-enamide
Mutant EGFR inhibitor |
| Description | Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M. |
|---|---|
| Related Catalog | |
| Target |
EGFRL858R EGFRExon 19 deletion EGFRT790M |
| References |
[1]. WO 2013014448 A1 |
| Molecular Formula | C27H30ClN7O2 |
|---|---|
| Molecular Weight | 520.02600 |
| Exact Mass | 519.21500 |
| PSA | 98.41000 |
| LogP | 5.29880 |
| Storage condition | 2-8℃ |