40788-84-9

40788-84-9 structure

Name: Isoviolanthin
Chemical Name: 6-C-Rhamnosyl-8-C-glucosylapigenin
CAS Number: 40788-84-9
Molecular Formula: C₂₇H₃₀O₁₄
Molecular Weight: 578.51900
Catalog: Research Areas Cancer
Create Date: 2018-05-18 23:49:44
Modify Date: 2024-01-14 11:03:47
Isoviolanthin is a flavonoid glycoside extracted from the leaves of Dendrobium officinale. Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells but exhibits no cytotoxic effects on normal live cells, and has potential as a therapeutic agent for the treatment of advanced-stage metastatic HCC[1].

Name	6-C-Rhamnosyl-8-C-glucosylapigenin
Synonyms	5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-6-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yl)-chromen-4-one

Description	Isoviolanthin is a flavonoid glycoside extracted from the leaves of Dendrobium officinale. Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells but exhibits no cytotoxic effects on normal live cells, and has potential as a therapeutic agent for the treatment of advanced-stage metastatic HCC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19(6).

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