Isoviolanthin

Modify Date: 2024-01-14 11:03:47

Isoviolanthin Structure
Isoviolanthin structure
Common Name Isoviolanthin
CAS Number 40788-84-9 Molecular Weight 578.51900
Density N/A Boiling Point N/A
Molecular Formula C27H30O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Isoviolanthin


Isoviolanthin is a flavonoid glycoside extracted from the leaves of Dendrobium officinale. Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells but exhibits no cytotoxic effects on normal live cells, and has potential as a therapeutic agent for the treatment of advanced-stage metastatic HCC[1].

 Names

Name 6-C-Rhamnosyl-8-C-glucosylapigenin
Synonym More Synonyms

 Isoviolanthin Biological Activity

Description Isoviolanthin is a flavonoid glycoside extracted from the leaves of Dendrobium officinale. Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells but exhibits no cytotoxic effects on normal live cells, and has potential as a therapeutic agent for the treatment of advanced-stage metastatic HCC[1].
Related Catalog
References

[1]. Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19(6).

 Chemical & Physical Properties

Molecular Formula C27H30O14
Molecular Weight 578.51900
Exact Mass 578.16400
PSA 250.97000

 Safety Information

Hazard Codes Xi

 Synonyms

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-6-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yl)-chromen-4-one
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